{"id":26495,"date":"2024-07-12T10:26:12","date_gmt":"2024-07-12T01:26:12","guid":{"rendered":"https:\/\/c-mng.cwh.hokudai.ac.jp\/www2.fish\/Root\/?p=26495"},"modified":"2024-07-12T10:26:12","modified_gmt":"2024-07-12T01:26:12","slug":"%e3%80%90%e3%83%97%e3%83%ac%e3%82%b9%e3%83%aa%e3%83%aa%e3%83%bc%e3%82%b9%e3%80%91%e9%ad%9a%e3%81%ae%e7%b2%be%e5%b7%a3%e3%83%bb%e5%8d%b5%e5%b7%a3%e3%81%8c%e3%81%bf%e3%82%93%e3%81%aa%e7%a9%ba%e3%81%a3","status":"publish","type":"post","link":"https:\/\/c-mng.cwh.hokudai.ac.jp\/www2.fish\/Root\/infomation\/26495","title":{"rendered":"\u3010\u30d7\u30ec\u30b9\u30ea\u30ea\u30fc\u30b9\u3011\u9b5a\u306e\u7cbe\u5de3\u30fb\u5375\u5de3\u304c\u307f\u3093\u306a\u7a7a\u3063\u307d\u306b\uff01\uff1f\uff5e\u6c4e\u7528\u6027\u306e\u9ad8\u3044\u9b5a\u985e\u306e\u4e0d\u598a\u5316\u6280\u8853\u3092\u958b\u767a\uff5e\uff08\u6c34\u7523\u79d1\u5b66\u7814\u7a76\u9662\u3000\u52a9\u6559\u3000\u897f\u6751\u4fca\u54c9\u3001\u6559\u6388\u3000\u85e4\u672c\u8cb4\u53f2\uff09"},"content":{"rendered":"
2024\u5e747\u670811\u65e5<\/p>\n
\u25cfCRISPR-Cas13d\u30b7\u30b9\u30c6\u30e0\u3092\u5229\u7528\u3057\u305f\u6c4e\u7528\u6027\u306e\u9ad8\u3044\u9b5a\u985e\u306e\u4e0d\u598a\u5316\u6280\u8853\u3092\u958b\u767a\u3002
\n\u25cf\u5b9f\u9a13\u30e2\u30c7\u30eb\u9b5a\u3067\u3042\u308b\u30e1\u30c0\u30ab\u3068\u7523\u696d\u91cd\u8981\u9b5a\u7a2e\u3067\u3042\u308b\u30cb\u30b8\u30de\u30b9\u3092\u9ad8\u3044\u52b9\u7387\u3067\u4e0d\u598a\u5316\u3055\u305b\u308b\u3053\u3068\u306b\u6210\u529f\u3002
\n\u25cf\u5916\u6765\u9b5a\u3084\u990a\u6b96\u9b5a\u306e\u8fc5\u901f\u304b\u3064\u78ba\u5b9f\u306a\u4e0d\u598a\u5316\u306b\u671f\u5f85\u3002<\/p>\n
<\/p>\n
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\u7814\u7a76\u30b0\u30eb\u30fc\u30d7\u306f\u3001\u8fd1\u5e74\u958b\u767a\u3055\u308c\u305fCRISPR-Cas13d\u30b7\u30b9\u30c6\u30e0\u306b\u7740\u76ee\u3057\u307e\u3057\u305f\u3002\u30b2\u30ce\u30e0\u7de8\u96c6\u6280\u8853\u3068\u3057\u3066\u77e5\u3089\u308c\u308bCRISPR-Cas9\u30b7\u30b9\u30c6\u30e0\u3067\u306f\u3001\u72d9\u3063\u305fDNA\uff08\u30b2\u30ce\u30e0\uff09\u3092\u5207\u65ad\u3057\u5909\u7570\u3092\u5c0e\u5165\u3067\u304d\u308b\u306e\u306b\u5bfe\u3057\u3001CRISPR-Cas13d\u30b7\u30b9\u30c6\u30e0\u3067\u306f\u3001\u72d9\u3063\u305fRNA\u3092\u5207\u65ad\u3057\u5206\u89e3\u3055\u305b\u308b\u3053\u3068\u304c\u53ef\u80fd\u3067\u3059\u3002\u6a19\u7684\u3068\u306a\u308bRNA\u306b\u7d50\u5408\u3059\u308b\u30ac\u30a4\u30c9RNA(gRNA)\u306e\u8a2d\u8a08\u306b\u5236\u7d04\u304c\u5c0f\u3055\u3044\u305f\u3081\u3001\u751f\u6b96\u7d30\u80de\u5f62\u6210\u306b\u5fc5\u8981\u306a\u907a\u4f1d\u5b50\u306e\u9b5a\u985e\u5171\u901a\u914d\u5217\u3092\u6a19\u7684\u3068\u3057\u305fgRNA\u3092\u8a2d\u8a08\u3059\u308b\u3053\u3068\u3067\u3001\u6c4e\u7528\u7684\u306b\u9b5a\u985e\u306e\u4e0d\u598a\u5316\u304c\u53ef\u80fd\u306a\u306e\u3067\u306f\u306a\u3044\u304b\u3068\u8003\u3048\u307e\u3057\u305f\u3002<\/p>\n
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\u5f93\u6765\u3001\u9b5a\u7a2e\u3054\u3068\u306b\u907a\u4f1d\u5b50\u306eDNA\u914d\u5217\u3092\u8abf\u3079\u3066\u304b\u3089gRNA\u3092\u8a2d\u8a08\u3059\u308b\u5fc5\u8981\u304c\u3042\u308a\u307e\u3057\u305f\u3002\u672c\u7814\u7a76\u3067\u958b\u767a\u3057\u305f\u5171\u901agRNA\u306f\u3001\u5168\u9b5a\u7a2e\u306e\u534a\u5206\u4ee5\u4e0a\u306b\u9069\u7528\u3067\u304d\u308b\u53ef\u80fd\u6027\u304c\u3042\u308a\u307e\u3059\u3002\u305d\u306e\u305f\u3081\u3001\u672c\u7814\u7a76\u6210\u679c\u306f\u3001DNA\u914d\u5217\u304c\u4e0d\u660e\u306a\u5916\u6765\u9b5a\u3084\u65b0\u898f\u5c0e\u5165\u3059\u308b\u990a\u6b96\u9b5a\u3092\u8fc5\u901f\u304b\u3064\u78ba\u5b9f\u306b\u4e0d\u598a\u5316\u3067\u304d\u308b\u6280\u8853\u306b\u3064\u306a\u304c\u308a\u307e\u3059\u3002<\/p>\n
\u306a\u304a\u3001\u672c\u7814\u7a76\u6210\u679c\u306f\u30012024\u5e746\u670826\u65e5\uff08\u6c34\uff09\u516c\u958b\u306eAquaculture<\/i>\u8a8c\u306b\u63b2\u8f09\u3055\u308c\u307e\u3057\u305f\u3002<\/p>\n
\u8ad6\u6587\u540d\uff1aSterilization of fish through adaptable gRNAs targeting\u00a0dnd1<\/i>\u00a0using CRISPR-Cas13d System\uff08CRISPR-Cas13d\u30b7\u30b9\u30c6\u30e0\u306b\u304a\u3051\u308bdnd1<\/i>\u907a\u4f1d\u5b50\u306b\u5bfe\u3059\u308b\u5171\u901agRNA\u3092\u7528\u3044\u305f\u9b5a\u985e\u306e\u4e0d\u598a\u5316\uff09 <\/p>\n \u8a73\u7d30\u306f\u3053\u3061\u3089<\/a><\/p>\n \n
\nURL\uff1ahttps:\/\/doi.org\/10.1016\/j.aquaculture.2024.741269<\/a><\/p>\n