北海道大学 大学院水産科学研究院 大学院水産科学院 水産学部

英語サイトへ 北海道大学
教授
山羽 悦郎
やまは えつろう
  • 北方生物圏フィールド科学センター 
  • 七飯淡水実験所
オフィス
〒041-1105 北海道亀田郡七飯町桜町2−9−1
メール
eyamaha◎fsc.hokudai.ac.jp
※「◎」を「@」に変更
電話
0138-65-2344
研究課題
(1) 魚類の初期発生機構の研究
(2) 魚類の借腹生産に関する研究
(3) 魚類の発生工学に関する手法の開発
代表的な業績
  1. Yamaha, E. and Yamazaki, F.: Electrically fused-egg induction and its development in the goldfish, Carassius auratus.  Int. J. Dev. Biol., 37; 291-298 (1993).
  2. Mizuno, T., Yamaha, E., Wakahara, M., Kuroiwa, A. and Takeda, H.: Mesoderm induction in zebrafish embryos. Nature, 383: 131-132 (1996).
  3. Mizuno, T., Yamaha, E. and Yamazaki, F.: Localized axis determinant at the early cleavage stage embryo in the goldfish, Carassius auratus. Dev. Genes Evol., 206: 389-396 (1997).
  4. Yamaha, E., Mizuno, T., Hasebe, Y. and Yamazaki, F.: Chimeric fish produced by blastoderm exchange in goldfish, Carassius auratus. Fisheries Science, 63: 514-519 (1997).
  5. Yamaha, E., Mizuno, T., Hasebe, Y., Takeda, H. and Yamazaki, F.: Dorsal specification in the blastoderm at the blastula stage in goldfish, Carassius auratus. Develop. Growth Differ., 40: 267-275 (1998).
  6. Kazama-Wakabayashi, M., Yamaha, E. and Yamazaki, F.: The elimination and duplication of lower part of blastoderm effects on the number of primordial germ cells in goldfish.  Fisheries Sci., 65: 577-582 (1999).
  7. Yamaha, E., Kazama-Wakabayashi, M., Otani, S., Fujimoto, T. and Arai, K.: Germ-line chimera by blastoderm transplantation between diploid goldfish and triploid crucian carp.  Genetica, 111: 227-236 (2001).
  8. Otani, S., Maegawa, S., Inoue, K., Arai, K. and Yamaha, E.: The germ cell lineage identified by vas-mRNA during embryogenesis in goldfish. Zool. Sci., 19: 519-526 (2002).
  9. Yamaha, E., Murakami, M., Hada, K., Otani, S., Fujimoto, T., Tanaka, M., Sakao, S., Kimura, S., Sato, S. and Arai, K.: Recovery of fertility in male hybrids of a cross between goldfish and common carp by transplantation of PGCs (primordial germ cell)-containing graft.  Genetica, 119:121-131 (2003).
  10. Otani, S., Kitauchi, T., Sakao, S., Saito, T., Maegawa, S., Inoue, K., Arai, K., and Yamaha, E.: The formation of PGCs from the germline cells in spherical embryos derived from the blastodisc of 2-cell embryos in goldfish, Carassius auratus.  Int. J. Dev. Biol.  49: 843-850 (2005)
  11. Saito, T., Fujimoto, T., Maegawa, S., Inoue, K., Tanaka, M., Arai, K. and Yamaha, E.: Visualization of primordial germ cells in vivo using GFP-nos1 3'UTR mRNA. Int. J. Dev. Biol.  50: 691-700 (2006)
  12. Yamaha, E., Saito, T., Goto-Kazeto, R. and Arai, K.: Developmental biotechnology for aquaculture, with special reference to surrogate production in teleost fishes.  J. Sea Res. 58:8-22. (2007)
  13. Saito, T., Goto-Kazeto, R., Arai, K., Yamaha, E.: Xenogenesis in teleost fish through generation of germ-line chimeras by single primordial germ cell transplantation.  Biol. Reprod. 78: 159-166 (2008)
  14. Fujimoto, T., Saito, T., Sakao, S., Arai, K. and Yamaha, E.  Developmental potential of embryonic cells in a nucleo-cytoplasmic hybrid formed using a goldfish haploid nucleus and loach egg cytoplasm. Int. J. Dev. Biol. 54: 827-835 (2010).
  15. Fujimoto, T., Nishimura, T., Goto-Kazeto, R., Kawakami, Y., Yamaha, E. and Arai, K.  Sexual dimorphism of gonadal structure and gene expression in germ cell deficient loach, a teleost fish. Proc. Ntl. Acad. Sci. USA  107(40):17211-6 (2010)
  16. Saito, T., Goto-Kazeto, R., Fujimoto, T., Kawakami, Y., Arai, K. and Yamaha, E. Inter-species transplantation and migration of primordial germ cells in cyprinid fish. Int. J. Dev. Biol. 54:1481-1486 (2010)[In Press] doi: 10.1387/ijdb.103111ts
  17. Saito, T., Goto-Kazeto, R., Kawakami, Y., Nomura, K., Tanaka, H., Adachi, S., Arai, K. and Yamaha, E. The mechanism for primordial germ-cell migration is conserved between Japanese eel and zebrafish. PLoS ONE 6 (9): p1. (2011)
  18. Kitauchi, T., Saito, T., Motomura, T., Arai, K., Yamaha, E. (2012). Distribution and function of germ plasm in cytoplasmic fragments from centrifuged eggs of the goldfish, Carassius auratus. Journal of Applied Ichthyology. 28, 998–1005.
  19. Goto R, Saito T, Takeda T, Fujimoto T, Takagi M, Arai K, Yamaha E. Germ cells are not the primary factor for sexual fate determination in goldfish. Developmental Biology, 370, 98-109 (2012).
  20. Tzung K-W, Goto R., Saju JM., Sreenivasan R., Saito T., Arai K., Yamaha E., Hossain MS, Calvert M. EK,   Orban, L. Early depletion of primordial germ cells in zebrafish promotes testis formation. Stem Cell Reports. 4:1-13 (2015)
  21. Yanagimachi, R., Harumi, T., Matsubara, H., Yan, W., Yuan, S., Hirohashi, N., Iida, T., Yamaha, E., Arai, K., Matsubara, T., Andoh, T., Vines, C., Cherr, G. (2017).  Chemical and physical guidance of fish spermatozoa into the egg through the micropyle. Biol. Reprod. 96(4):780-799.
担当授業
学部
北方水圏機能生物学(分担)
水産生物学実験(分担)

大学院(環境科学院)
生物生産学基礎論
水圏生物学特論Ⅰ
略歴
昭和 56 年 4 月	北海道大学大学院水産学研究科修士課程入学
昭和 60 年 12月  北海道大学水産学部助手に採用
平成  7 年  4月 	北海道大学水産学部附属七飯養魚実習施設へ助手として配置換
平成 10 年  4月	北海道大学水産学部助教授
平成 13 年 4月	北海道大学北方生物圏フィールド科学センター助教授
平成 15 年 4月	北海道大学北方生物圏フィールド科学センター教授
受賞
平成21年度 日本水産学会論文賞
教員からのメッセージ
魚を養殖することで人間は確保しています。より生産性が高く、より品質の高い魚を作るため、様々な技術開発が世界中で行われてきています。その一方で、養殖用の餌となる魚が減少し、養殖魚の病気が広がり、さらには環境が悪化している現状が有ります。限られた空間で魚だけを養殖するのでは、これらの問題は解決できないと考えています。魚の研究としての水産学に、農学や畜産学などの分野を加え、多方面からこれらの問題を解決する事が必要です。広い視野を持って問題解決のできる人を目指して下さい。

北海道大学研究者総覧システムへ
YAMAHA Etsuro
  • Professor of Field Science Center for Northern Biosphere
  • Section of Biodiversity
  • Director of Nanae Fresh-Water Station
Office location
2-9-1, Nanae, Kameda, Hokkaido, 041-1105 Japan
Email
eyamaha[at]fsc.hokudai.ac.jp
※ change [at] to @
Phone
+81-138-65-2344
Research Areas
Study on Embryology in teleost.
Development of developmental biotechnology
Surrogate propagation of teleost.
Representative publications
  1. Yamaha, E. and Yamazaki, F.: Electrically fused-egg induction and its development in the goldfish, Carassius auratus.  Int. J. Dev. Biol., 37; 291-298 (1993).
  2. Mizuno, T., Yamaha, E., Wakahara, M., Kuroiwa, A. and Takeda, H.: Mesoderm induction in zebrafish embryos. Nature, 383: 131-132 (1996).
  3. Mizuno, T., Yamaha, E. and Yamazaki, F.: Localized axis determinant at the early cleavage stage embryo in the goldfish, Carassius auratus. Dev. Genes Evol., 206: 389-396 (1997).
  4. Yamaha, E., Mizuno, T., Hasebe, Y. and Yamazaki, F.: Chimeric fish produced by blastoderm exchange in goldfish, Carassius auratus. Fisheries Science, 63: 514-519 (1997).
  5. Yamaha, E., Mizuno, T., Hasebe, Y., Takeda, H. and Yamazaki, F.: Dorsal specification in the blastoderm at the blastula stage in goldfish, Carassius auratus. Develop. Growth Differ., 40: 267-275 (1998).
  6. Kazama-Wakabayashi, M., Yamaha, E. and Yamazaki, F.: The elimination and duplication of lower part of blastoderm effects on the number of primordial germ cells in goldfish.  Fisheries Sci., 65: 577-582 (1999).
  7. Yamaha, E., Kazama-Wakabayashi, M., Otani, S., Fujimoto, T. and Arai, K.: Germ-line chimera by blastoderm transplantation between diploid goldfish and triploid crucian carp.  Genetica, 111: 227-236 (2001).
  8. Otani, S., Maegawa, S., Inoue, K., Arai, K. and Yamaha, E.: The germ cell lineage identified by vas-mRNA during embryogenesis in goldfish. Zool. Sci., 19: 519-526 (2002).
  9. Yamaha, E., Murakami, M., Hada, K., Otani, S., Fujimoto, T., Tanaka, M., Sakao, S., Kimura, S., Sato, S. and Arai, K.: Recovery of fertility in male hybrids of a cross between goldfish and common carp by transplantation of PGCs (primordial germ cell)-containing graft.  Genetica, 119:121-131 (2003).
  10. Otani, S., Kitauchi, T., Sakao, S., Saito, T., Maegawa, S., Inoue, K., Arai, K., and Yamaha, E.: The formation of PGCs from the germline cells in spherical embryos derived from the blastodisc of 2-cell embryos in goldfish, Carassius auratus.  Int. J. Dev. Biol.  49: 843-850 (2005)
  11. Saito, T., Fujimoto, T., Maegawa, S., Inoue, K., Tanaka, M., Arai, K. and Yamaha, E.: Visualization of primordial germ cells in vivo using GFP-nos1 3'UTR mRNA. Int. J. Dev. Biol.  50: 691-700 (2006)
  12. Yamaha, E., Saito, T., Goto-Kazeto, R. and Arai, K.: Developmental biotechnology for aquaculture, with special reference to surrogate production in teleost fishes.  J. Sea Res. 58:8-22. (2007)
  13. Saito, T., Goto-Kazeto, R., Arai, K., Yamaha, E.: Xenogenesis in teleost fish through generation of germ-line chimeras by single primordial germ cell transplantation.  Biol. Reprod. 78: 159-166 (2008)
  14. Fujimoto, T., Saito, T., Sakao, S., Arai, K. and Yamaha, E.  Developmental potential of embryonic cells in a nucleo-cytoplasmic hybrid formed using a goldfish haploid nucleus and loach egg cytoplasm. Int. J. Dev. Biol. 54: 827-835 (2010).
  15. Fujimoto, T., Nishimura, T., Goto-Kazeto, R., Kawakami, Y., Yamaha, E. and Arai, K.  Sexual dimorphism of gonadal structure and gene expression in germ cell deficient loach, a teleost fish. Proc. Ntl. Acad. Sci. USA  107(40):17211-6 (2010)
  16. Saito, T., Goto-Kazeto, R., Fujimoto, T., Kawakami, Y., Arai, K. and Yamaha, E. Inter-species transplantation and migration of primordial germ cells in cyprinid fish. Int. J. Dev. Biol. 54:1481-1486 (2010)[In Press] doi: 10.1387/ijdb.103111ts
  17. Saito, T., Goto-Kazeto, R., Kawakami, Y., Nomura, K., Tanaka, H., Adachi, S., Arai, K. and Yamaha, E. The mechanism for primordial germ-cell migration is conserved between Japanese eel and zebrafish. PLoS ONE 6 (9): p1. (2011)
  18. Kitauchi, T., Saito, T., Motomura, T., Arai, K., Yamaha, E. (2012). Distribution and function of germ plasm in cytoplasmic fragments from centrifuged eggs of the goldfish, Carassius auratus. Journal of Applied Ichthyology. 28, 998–1005.
  19. Goto R, Saito T, Takeda T, Fujimoto T, Takagi M, Arai K, Yamaha E. Germ cells are not the primary factor for sexual fate determination in goldfish. Developmental Biology, 370, 98-109 (2012).
  20. Tzung K-W, Goto R., Saju JM., Sreenivasan R., Saito T., Arai K., Yamaha E., Hossain MS, Calvert M. EK,   Orban, L. Early depletion of primordial germ cells in zebrafish promotes testis formation. Stem Cell Reports. 4:1-13 (2015)
  21. Yanagimachi, R., Harumi, T., Matsubara, H., Yan, W., Yuan, S., Hirohashi, N., Iida, T., Yamaha, E., Arai, K., Matsubara, T., Andoh, T., Vines, C., Cherr, G. (2017).  Chemical and physical guidance of fish spermatozoa into the egg through the micropyle. Biol. Reprod. 96(4):780-799.

 

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